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Redox Platforms in Cancer Drug Discovery and Development

Redox homeostasis is frequently dysregulated in human disease, particularly cancer. Recent and ongoing efforts seek to validate and extend this platform for the discovery/development of anticancer drugs. As the primary source of cellular redox buffer, thiols (in particular glutathione) have been the...

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Detalhes bibliográficos
Main Authors: Tew, Kenneth D., Townsend, Danyelle M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073687/
https://ncbi.nlm.nih.gov/pubmed/21075043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.10.016
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