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Hesperetin, a Potential Therapy for Carcinoid Cancer

BACKGROUND: Our laboratory has demonstrated that the Notch1 signaling pathway acts as a tumor suppressor in carcinoids. In this study we examined hesperetin, a flavinoid, as a potential Notch1 activator and carcinoid tumor suppressor. METHODS: A high throughput drug screen revealed hesperetin as a N...

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Hlavní autoři: Zarebczan, Barbara, Pinchot, Scott N., Kunnimalaiyaan, Muthusamy, Chen, Herbert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073682/
https://ncbi.nlm.nih.gov/pubmed/21367373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjsurg.2010.08.018
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