Expression of SLCO transport genes in castration resistant prostate cancer and impact of genetic variation in SCLO1B3 and SLCO2B1 on prostate cancer outcomes

BACKGROUND: Metastases from men with castration resistant prostate cancer (CRPC) harbor increased tumoral androgens vs. untreated prostate cancers (PCa). This may reflect steroid uptake by OATP/SLCO transporters. We evaluated SLCO gene expression in CRPC metastases and determined whether PCa outcome...

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Hauptverfasser: Wright, Jonathan L, Kwon, Erika M, Ostrander, Elaine A, Montgomery, R Bruce, Lin, Daniel W, Vessella, Robert, Stanford, Janet L, Mostaghel, Elahe A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073610/
https://ncbi.nlm.nih.gov/pubmed/21266523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-1023
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