Enhanced Detection of Chromosomal Abnormalities in Chronic Lymphocytic Leukemia by Conventional Cytogenetics Using CpG Oligonucleotide in Combination with Pokeweed Mitogen and Phorbol Myristate Acetate

Reproducible cytogenetic analysis in CLL has been limited by the inability to obtain reliable metaphase cells for analysis. CpG oligonucleotide and cytokine stimulation have been shown to improve metaphase analysis of CLL cytogenetic abnormalities, but is limited by variability in the cytokine recep...

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Main Authors: Muthusamy, Natarajan, Breidenbach, Heather, Andritsos, Leslie, Flynn, Joseph, Jones, Jeffrey, Ramanunni, Asha, Mo, Xiaokui, Jarjoura, David, Byrd, John C., Heerema, Nyla A.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073597/
https://ncbi.nlm.nih.gov/pubmed/21494579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2010.12.006
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