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Lopinavir/Ritonavir Pharmacokinetic Profile: Impact of Sex and Other Covariates Following a Change From Twice-Daily to Once-Daily Therapy

The aim of this study was to determine the impact of sex on the pharmacokinetics of lopinavir/ritonavir. Interaction between lopinavir/ritonavir and tenofovir was also evaluated. Steady-state plasma samples were obtained from virologically suppressed HIV-infected patients on lopinavir/ritonavir 800/...

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Autors principals: Ofotokun, Ighovwerha, Chuck, Susan K., Binongo, Jose N., Palau, Mauricio, Lennox, Jeffrey L., Acosta, Edward P.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073482/
https://ncbi.nlm.nih.gov/pubmed/17615254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270007302564
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