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An oligodeoxyribonucleotide that supports catalytic activity in the hammerhead ribozyme domain.

A study of the activity of deoxyribonucleotide-substituted analogs of the hammerhead domain of RNA catalysis has led to the design of a 14mer oligomer composed entirely of deoxyribonucleotides that promotes the cleavage of an RNA substrate. Characterization of this reaction with sequence variants an...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Chartrand, P, Harvey, S C, Ferbeyre, G, Usman, N, Cedergren, R
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1995
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307348/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.20.4092
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