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An oligodeoxyribonucleotide that supports catalytic activity in the hammerhead ribozyme domain.

A study of the activity of deoxyribonucleotide-substituted analogs of the hammerhead domain of RNA catalysis has led to the design of a 14mer oligomer composed entirely of deoxyribonucleotides that promotes the cleavage of an RNA substrate. Characterization of this reaction with sequence variants an...

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Main Authors: Chartrand, P, Harvey, S C, Ferbeyre, G, Usman, N, Cedergren, R
Format: Artigo
Jezik:Inglês
Izdano: 1995
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC307348/
https://ncbi.nlm.nih.gov/pubmed/7479070
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