Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice

Low-grade inflammation in different tissues, including activation of the nuclear factor κB pathway in liver, is involved in metabolic disorders such as type 2 diabetes and cardiovascular diseases (CVDs). In this study, we investigated the relation between chronic hepatocyte-specific overexpression o...

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Hlavní autoři: van Diepen, Janna A., Wong, Man C., Guigas, Bruno, Bos, Jasper, Stienstra, Rinke, Hodson, Leanne, Shoelson, Steven E., Berbée, Jimmy F. P., Rensen, Patrick C. N., Romijn, Johannes A., Havekes, Louis M., Voshol, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2011
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073472/
https://ncbi.nlm.nih.gov/pubmed/21357939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M010405
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