Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice

Low-grade inflammation in different tissues, including activation of the nuclear factor κB pathway in liver, is involved in metabolic disorders such as type 2 diabetes and cardiovascular diseases (CVDs). In this study, we investigated the relation between chronic hepatocyte-specific overexpression o...

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Detalhes bibliográficos
Main Authors: van Diepen, Janna A., Wong, Man C., Guigas, Bruno, Bos, Jasper, Stienstra, Rinke, Hodson, Leanne, Shoelson, Steven E., Berbée, Jimmy F. P., Rensen, Patrick C. N., Romijn, Johannes A., Havekes, Louis M., Voshol, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073472/
https://ncbi.nlm.nih.gov/pubmed/21357939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M010405
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