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Acquisition of regulatory function by human CD8+ T cells treated with anti-CD3 antibody requires TNF
Anti-CD3 monoclonal antibodies can modulate graft rejection and attenuate autoimmune diseases but their mechanism(s) of action remain unclear. CD8+ T cells with regulatory function are induced in vitro by Teplizumab, a humanized anti-CD3 antibody and inhibit responses of autologous and allogeneic T...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073342/ https://ncbi.nlm.nih.gov/pubmed/21038470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040485 |
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