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New insights into repeat instability: Role of RNA•DNA hybrids

Expansion of tandem repeat sequences is responsible for more than 20 human diseases. Several cis elements and trans factors involved in repeat instability (expansion and contraction) have been identified. However no comprehensive model explaining large intergenerational or somatic changes of the len...

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Autori principali: McIvor, Elizabeth I, Polak, Urszula, Napierala, Marek
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073251/
https://ncbi.nlm.nih.gov/pubmed/20729633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.7.5.12745
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