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Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin

Human serum albumin (HSA) has two primary binding sites for drug molecules. These sites selectively bind different dansylated amino acid compounds, which—due to their intrinsic fluorescence—have long been used as specific markers for the drug pockets on HSA. We present here the co-crystal structures...

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Bibliografiske detaljer
Main Authors: Ryan, Ali J., Ghuman, Jamie, Zunszain, Patricia A., Chung, Chun-wa, Curry, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: Academic Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073228/
https://ncbi.nlm.nih.gov/pubmed/20940056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2010.10.004
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