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Sequences 5' of the first upstream open reading frame in GCN4 mRNA are required for efficient translational reinitiation.

Translation of yeast GCN4 mRNA occurs by a reinitiation mechanism that is modulated by amino acid levels in the cell. Ribosomes which translate the first of four upstream open reading frames (uORFs) in the mRNA leader resume scanning and can reinitiate downstream. Under non-starvation conditions rei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grant, C M, Miller, P F, Hinnebusch, A G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC307320/
https://ncbi.nlm.nih.gov/pubmed/7479046
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