Differential Role of DNA-PKcs Phosphorylations and Kinase Activity in Radiosensitivity and Chromosomal Instability

The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is the key functional element in the DNA-PK complex that drives nonhomologous end joining (NHEJ), the predominant DNA double-strand break (DSB) repair mechanism operating to rejoin such breaks in mammalian cells after exposure to ioniz...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Nagasawa, Hatsumi, Little, John B., Lin, Yu-Fen, So, Sairei, Kurimasa, Akihiro, Peng, Yuanlin, Brogan, John R., Chen, David J., Bedford, Joel S., Chen, Benjamin P. C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073160/
https://ncbi.nlm.nih.gov/pubmed/21175350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR2092.1
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller