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In vitro activity of minimised hammerhead ribozymes.
A number of minimised hammerhead ribozymes (minizymes) which lack stem II have been kinetically characterised. These minizymes display optimal cleavage activity at temperatures around 37 degrees C. The cleavage reactions of the minizymes are first order in hydroxide ion concentration up to around pH...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1995
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307311/ https://ncbi.nlm.nih.gov/pubmed/7479037 |
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