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Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents.

Previously, mouse NIH 3T3 cells were stably transfected with human DNA polymerase beta (beta-pol) cDNA in the antisense orientation and under the control of a metallothionein promoter [Zmudzka, B.Z. and Wilson, S.H. (1990) Som. Cell Mol. Gen., 16, 311-320]. To assess the feasibility of enhancing the...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Horton, J K, Srivastava, D K, Zmudzka, B Z, Wilson, S H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 1995
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307295/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.19.3810
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