Memory B cells from a subset of treatment naïve relapsing remitting multiple sclerosis patients elicit CD4+ T cell proliferation and IFN-γ production in response to MBP and MOG

Recent evidence suggests that B and T cell interactions may be paramount in relapsing remitting multiple sclerosis (RRMS) disease pathogenesis. We hypothesized that memory B cell pools from RRMS patients may specifically harbor a subset of potent neuro-antigen presenting cells that support neuro-ant...

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Hlavní autoři: Harp, Christopher T., Ireland, Sara, Davis, Laurie S., Remington, Gina, Cassidy, Bonnie, Cravens, Petra D., Stuve, Olaf, Lovett-Racke, Amy E., Eagar, Todd N., Greenberg, Benjamin M., Racke, Michael K., Cowell, Lindsay G., Karandikar, Nitin J., Frohman, Elliot M., Monson, Nancy L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072802/
https://ncbi.nlm.nih.gov/pubmed/20812237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040516
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