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The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1
DMF (dimethyl fumarate) exerts anti-inflammatory and pro-metabolic effects in a variety of cell types, and a formulation (BG-12) is being evaluated for monotherapy in multiple sclerosis patients. DMF modifies glutathione (GSH) levels that can induce expression of the anti-inflammatory protein HO-1 (...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Neurochemistry
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072764/ https://ncbi.nlm.nih.gov/pubmed/21382015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20100033 |
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