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TIF1γ controls erythroid cell fate by regulating transcription elongation

Recent genome-wide studies have demonstrated pausing of RNA polymerase II (Pol II) occurred on many vertebrate genes. By genetic studies in the zebrafish tif1γ mutant moonshine we found that loss of function of Pol II-associated factors PAF or DSIF rescued erythroid gene transcription in tif1γ-defic...

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Main Authors: Bai, Xiaoying, Kim, Jonghwan, Yang, Zhongan, Jurynec, Michael J., Akie, Thomas E., Lee, Joseph, LeBlanc, Jocelyn, Sessa, Anna, Jiang, Hong, DiBiase, Anthony, Zhou, Yi, Grunwald, David J., Lin, Shuo, Cantor, Alan B., Orkin, Stuart H., Zon, Leonard I.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072682/
https://ncbi.nlm.nih.gov/pubmed/20603019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.05.028
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