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Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment

Inhibitors of proteasomes have been shown to affect endocytosis of multiple membrane receptors, in particular at the step of cargo sorting for lysosomal degradation. Here we demonstrate that the inhibition of proteasomes causes specific redistribution of an endosomal adaptor APPL1, which undergoes i...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pilecka, Iwona, Sadowski, Lukasz, Kalaidzidis, Yannis, Miaczynska, Marta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Academic Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072527/
https://ncbi.nlm.nih.gov/pubmed/21320486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.02.002
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