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Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication
We performed experiments to determine the effect of PKR activation on respiratory syncytial virus (RSV) replication. We first determined that RSV infection activates PKR which induces the phosphorylation of eIF2α, resulting in the formation of host stress granules. We used RNA interference to decrea...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier Inc.
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072468/ https://ncbi.nlm.nih.gov/pubmed/21377708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.02.009 |
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