Profilin is required for viral morphogenesis, syncytium formation, and cell-specific stress fiber induction by respiratory syncytial virus

BACKGROUND: Actin is required for the gene expression and morphogenesis of respiratory syncytial virus (RSV), a clinically important Pneumovirus of the Paramyxoviridae family. In HEp-2 cells, RSV infection also induces actin stress fibers, which may be important in the immunopathology of the RSV dis...

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Bibliographic Details
Main Authors: Bitko, Vira, Oldenburg, Anja, Garmon, Nicolle E, Barik, Sailen
Format: Artigo
Language:Inglês
Published: BioMed Central 2003
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC156654/
https://ncbi.nlm.nih.gov/pubmed/12740026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-3-9
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