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Vaccination against nicotine alters the distribution of nicotine delivered via cigarette smoke inhalation to rats

Preclinical models of nicotine vaccine pharmacology have relied on i.v. or s.c. administration of nicotine. Models using cigarette smoke inhalation might more accurately simulate nicotine exposure in smokers. Nicotine vaccine effects were examined in rats using two cigarette smoke exposure models: a...

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Hlavní autoři: Pravetoni, M, Keyler, DE, Raleigh, MD, Harris, AC, LeSage, MG, Mattson, CK, Pettersson, S, Pentel, PR
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072463/
https://ncbi.nlm.nih.gov/pubmed/21333633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.02.004
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