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Twist1-induced invadopodia formation promotes tumor metastasis
The Twist1 transcription factor is known to promote tumor metastasis and induce Epithelial-Mesenchymal Transition (EMT). Here, we report that Twist1 is capable of promoting the formation of invadopodia, specialized membrane protrusions for extracellular matrix degradation. Twist1 induces PDGFRα expr...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072410/ https://ncbi.nlm.nih.gov/pubmed/21397860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.01.036 |
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