5-Azacytidine promotes invadopodia formation and tumor metastasis through the upregulation of PI3K in ovarian cancer cells

The high incidence of metastasis accounts for most of the lethality of ovarian cancer. Invadopodia are small, specialized types of machinery that degrade the extracellular matrix and are thus involved in the invasion and metastasis of cancer cells. The formation of invadopodia is regulated by both g...

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Udgivet i:Oncotarget
Main Authors: Cao, Dan, Li, Dan, Huang, Yong, Ma, Yu, Zhang, Binglan, Zhao, Chengjian, Deng, Senyi, Luo, Min, Yin, Tao, Wei, Yu-Quan, Wang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601130/
https://ncbi.nlm.nih.gov/pubmed/28947962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18580
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