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Survival Motor Neuron Protein Regulates Stem Cell Division, Proliferation, and Differentiation in Drosophila

Spinal muscular atrophy is a severe neurogenic disease that is caused by mutations in the human survival motor neuron 1 (SMN1) gene. SMN protein is required for the assembly of small nuclear ribonucleoproteins and a dramatic reduction of the protein leads to cell death. It is currently unknown how t...

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Detalhes bibliográficos
Main Authors: Grice, Stuart J., Liu, Ji-Long
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072375/
https://ncbi.nlm.nih.gov/pubmed/21490958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002030
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