The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation

The ubiquitin proteasome system (UPS) plays an important role in regulating numerous cellular processes, and a dysfunctional UPS is thought to contribute to motor neuron disease. Consequently, we sought to map the changing ubiquitome in human iPSCs during their pluripotent stage and following differ...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Bax, Monique, McKenna, Jessie, Do-Ha, Dzung, Stevens, Claire H., Higginbottom, Sarah, Balez, Rachelle, Cabral-da-Silva, Mauricio e Castro, Farrawell, Natalie E., Engel, Martin, Poronnik, Philip, Yerbury, Justin J., Saunders, Darren N., Ooi, Lezanne
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627164/
https://ncbi.nlm.nih.gov/pubmed/31200561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060581
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