Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects

To better understand telomere biology in budding yeast, we have performed systematic suppressor/enhancer analyses on yeast strains containing a point mutation in the essential telomere capping gene CDC13 (cdc13-1) or containing a null mutation in the DNA damage response and telomere capping gene YKU...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Addinall, Stephen Gregory, Holstein, Eva-Maria, Lawless, Conor, Yu, Min, Chapman, Kaye, Banks, A. Peter, Ngo, Hien-Ping, Maringele, Laura, Taschuk, Morgan, Young, Alexander, Ciesiolka, Adam, Lister, Allyson Lurena, Wipat, Anil, Wilkinson, Darren James, Lydall, David
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2011
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072368/
https://ncbi.nlm.nih.gov/pubmed/21490951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001362
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