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Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels

In traditional folk medicine, Xanthoxylum plants are referred to as ‘toothache trees’ because their anesthetic or counter-irritant properties render them useful in the treatment of pain. Psychophysical studies have identified hydroxy-α-sanshool as the compound most responsible for the unique tinglin...

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Detalhes bibliográficos
Main Authors: Bautista, Diana M, Sigal, Yaron M, Milstein, Aaron D, Garrison, Jennifer L, Zorn, Julie A, Tsuruda, Pamela R, Nicoll, Roger A, Julius, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072296/
https://ncbi.nlm.nih.gov/pubmed/18568022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2143
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