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Endothelin-1 raises excitability and reduces potassium currents in sensory neurons

Exposure to endothelin-1 (ET-1, 50nM) of sensory neurons, acutely isolated from rat dorsal root ganglia, results in an increase in the number of action potentials elicited by a linear ramp of stimulating current. The changes are complete in 5 minutes after ET-1 treatment and do not reverse in 5-10 m...

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Detalhes bibliográficos
Main Authors: Feng, Bihua, Strichartz, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703700/
https://ncbi.nlm.nih.gov/pubmed/19409452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2009.04.012
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