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The C-terminal acidic tail is responsible for the inhibitory effects of HMGB1 on efferocytosis
HMGB1 was described originally as a nuclear protein involved in DNA binding and transcriptional regulation. However, HMGB1 also has an extracellular role as a potent mediator of inflammation and can diminish the uptake of apoptotic cells by phagocytes, a process called efferocytosis. To explore the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072233/ https://ncbi.nlm.nih.gov/pubmed/20682624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0510262 |
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