HMGB1 inhibits macrophage activity in efferocytosis through binding to the α(v)β(3)-integrin

Phagocytosis of apoptotic cells is critical to resolution of inflammation. High mobility group box 1 protein (HMGB1), a mediator of inflammation, has been shown to diminish phagocytosis through binding to phosphatidylserine (PS) exposed on the surface of apoptotic neutrophils. However, it is current...

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Dettagli Bibliografici
Autori principali: Friggeri, Arnaud, Yang, Yanping, Banerjee, Sami, Park, Yong-Jun, Liu, Gang, Abraham, Edward
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
Soggetti:
Growth, Differentiation, and Apoptosis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006331/
https://ncbi.nlm.nih.gov/pubmed/20826760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00152.2010
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