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Mucosal Human Defensins 5 and 6 Antagonize the Anti-HIV Activity of Candidate Polyanion Microbicides

Defensins are highly abundant antimicrobial peptides in the female genital mucosa. We have previously shown that human defensins 5 and 6 (HD5 and HD6), produced by cervicovaginal epithelial cells, significantly enhance HIV infectivity in vitro. Candidate polyanion microbicides, including PRO 2000, c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ding, Jian, Rapista, Aprille, Teleshova, Natalia, Lu, Wuyuan, Klotman, Mary E., Chang, Theresa L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: S. Karger AG 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072205/
https://ncbi.nlm.nih.gov/pubmed/21160168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000322355
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