Human Alpha-Defensin HNP1 Increases HIV Traversal of the Epithelial Barrier: A Potential Role in STI-Mediated Enhancement of HIV Transmission

Alpha-defensins, including human neutrophil peptides 1-3 (HNP1-3) and human defensin 5 (HD5), are elevated at the genital mucosa in individuals with sexually transmitted infections (STIs). The presence of STIs is associated with an increased risk of human immunodeficiency virus (HIV) transmission, s...

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Publicat a:Viral Immunol
Autors principals: Valere, Kimyata, Rapista, Aprille, Eugenin, Eliseo, Lu, Wuyuan, Chang, Theresa L.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2015
Matèries:
Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677513/
https://ncbi.nlm.nih.gov/pubmed/26379091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2014.0137
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