Variable pause positions of RNA polymerase II lie proximal to the c-myc promoter irrespective of transcriptional activity.

Transcriptional activation of the c-myc proto-oncogene is mediated by the transition of promoter proximal, paused RNA polymerase II (pol II) into a processive transcription mode. Using a transcription assay which allows the high resolution mapping of transcriptional complexes in intact nuclei, we ha...

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Bibliographic Details
Main Authors: Wolf, D A, Strobl, L J, Pullner, A, Eick, D
Format: Artigo
Language:Inglês
Published: 1995
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC307213/
https://ncbi.nlm.nih.gov/pubmed/7567445
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