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Transition from initiation to promoter proximal pausing requires the CTD of RNA polymerase II
The C-terminal domain (CTD) of mammalian RNA polymerase II consists of 52 repeats of the consensus hepta-peptide YSPTSPS, and links transcription to the processing of pre-mRNA. Although Pol II with a CTD shortened to five repeats (Pol II Δ5) is transcriptionally inactive on chromatin templates, it i...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1214543/ https://ncbi.nlm.nih.gov/pubmed/16157863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki802 |
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