Multiple treatment cycles of Liposome-encapsulation of adenoviral RIP-TK gene therapy effectively ablate human pancreatic cancer cells in SCID mice

INTRODUCTION: Adenoviral gene therapy has been widely applied for cancer therapy, however, transient gene expression as result of humoral immuno-neutralization response to adenovirus limits its effect. The purpose of this study is to determine whether DOTAP:cholesterol liposome could shield adenovir...

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Main Authors: Liu, Shi-He, Smyth-Templeton, Nancy, Davis, Alan R., Davis, Elizabeth A., Ballian, Nikiforos, Li, Min, Liu, Hao, Fisher, William, Brunicardi, F. Charles
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072061/
https://ncbi.nlm.nih.gov/pubmed/21295812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.11.014
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