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Multiple treatment cycles of Liposome-encapsulation of adenoviral RIP-TK gene therapy effectively ablate human pancreatic cancer cells in SCID mice
INTRODUCTION: Adenoviral gene therapy has been widely applied for cancer therapy, however, transient gene expression as result of humoral immuno-neutralization response to adenovirus limits its effect. The purpose of this study is to determine whether DOTAP:cholesterol liposome could shield adenovir...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072061/ https://ncbi.nlm.nih.gov/pubmed/21295812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.11.014 |
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