Caricamento...

Intercalation of XR5944 with the estrogen response element is modulated by the tri-nucleotide spacer sequence between half-sites

DNA-intercalating molecules can impair DNA replication, DNA repair, and gene transcription. We previously demonstrated that XR5944, a DNA bis-intercalator, specifically blocks binding of estrogen receptor-α (ERα) to the consensus estrogen response element (ERE). The consensus ERE sequence is AGGTCAn...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Sidell, Neil, Mathad, Raveendra I., Shu, Feng-jue, Zhang, Zhenjiang, Kallen, Caleb B., Yang, Danzhou
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072055/
https://ncbi.nlm.nih.gov/pubmed/21333738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2011.02.003
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !