Cells lacking IκB kinase α (IKKα) demonstrate nuclear cyclin D1 overexpression and a neoplastic phenotype: Role of IKKα as a Tumor Suppressor

IKKα and IKKβ, catalytic subunits of IκB kinase (IKK) complex are involved in activation of NF-κB and in mediating a variety of other biological functions. Though these proteins have a high sequence homology, IKKα exhibits different functional characteristics as compared to IKKβ. Earlier, we have de...

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Detalhes bibliográficos
Main Authors: Kwak, Youn-Tae, Radaideh, Sofyan M, Ding, Lianghao, Li, Rui, Frenkel, Eugene, Story, Michael D, Girard, Luc, Minna, John, Verma, Udit N
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072035/
https://ncbi.nlm.nih.gov/pubmed/21317297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0248
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