Effects of spironolactone in spontaneously hypertensive adult rats subjected to high salt intake

OBJECTIVE: To evaluate the effect of spironolactone on ventricular stiffness in spontaneously hypertensive adult rats subjected to high salt intake. INTRODUCTION: High salt intake leads to cardiac hypertrophy, collagen accumulation and diastolic dysfunction. These effects are partially mediated by c...

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Autors principals: Baldo, Marcelo Perim, Zaniqueli, Divanei, Forechi, Ludimila, Machado, Rebeca Caldeira, Rodrigues, Sérgio Lamêgo, Mill, José Geraldo
Format: Artigo
Idioma:Inglês
Publicat: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072011/
https://ncbi.nlm.nih.gov/pubmed/21552676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1807-59322011000300020
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