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Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration

Zebrafish heart regeneration occurs through the activation of cardiomyocyte proliferation in areas of trauma. Here, we show that within three hours of ventricular injury, the entire endocardium undergoes morphological changes and induces expression of the retinoic acid (RA)-synthesizing enzyme raldh...

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Bibliografische gegevens
Hoofdauteurs: Kikuchi, Kazu, Holdway, Jennifer E., Major, Robert J., Blum, Nicola, Dahn, Randall D., Begemann, Gerrit, Poss, Kenneth D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071981/
https://ncbi.nlm.nih.gov/pubmed/21397850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.01.010
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