Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration

Zebrafish heart regeneration occurs through the activation of cardiomyocyte proliferation in areas of trauma. Here, we show that within three hours of ventricular injury, the entire endocardium undergoes morphological changes and induces expression of the retinoic acid (RA)-synthesizing enzyme raldh...

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Hlavní autoři: Kikuchi, Kazu, Holdway, Jennifer E., Major, Robert J., Blum, Nicola, Dahn, Randall D., Begemann, Gerrit, Poss, Kenneth D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071981/
https://ncbi.nlm.nih.gov/pubmed/21397850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.01.010
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