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Activity-Based Protein Profiling of Organophosphorus and Thiocarbamate Pesticides Reveals Multiple Serine Hydrolase Targets in Mouse Brain

Organophosphorus (OP) and thiocarbamate (TC) agrochemicals are used worldwide as insecticides, herbicides, and fungicides, but their safety assessment in terms of potential off-targets remains incomplete. In this study, we used a chemoproteomic platform, termed activity-based protein profiling, to b...

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Bibliografiske detaljer
Main Authors: NOMURA, DANIEL K., CASIDA, JOHN E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071868/
https://ncbi.nlm.nih.gov/pubmed/21341672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jf101747r
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