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Oxidative damage to 5-methylcytosine in DNA.
Exposure of pyrimidines of DNA to ionizing radiation under aerobic conditions or oxidizing agents results in attack on the 5,6 double bond of the pyrimidine ring or on the exocyclic 5-methyl group. The primary product of oxidation of the 5,6 double bond of thymine is thymine glycol, while oxidation...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1995
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307183/ https://ncbi.nlm.nih.gov/pubmed/7667100 |
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