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Ectopic Cdx2 Expression in Murine Esophagus Models an Intermediate Stage in the Emergence of Barrett's Esophagus

Barrett's esophagus (BE) is an intestinal metaplasia that occurs in the setting of chronic acid and bile reflux and is associated with a risk for adenocarcinoma. Expression of intestine-specific transcription factors in the esophagus likely contributes to metaplasia development. Our objective w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kong, Jianping, Crissey, Mary Ann, Funakoshi, Shinsuke, Kreindler, James L., Lynch, John P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071814/
https://ncbi.nlm.nih.gov/pubmed/21494671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018280
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