Novel human single chain antibody fragments that are rapidly interalizing effectively target epithelioid and sarcomatoid mesotheliomas

Human antibodies targeting all subtypes of mesothelioma could be useful to image and treat this deadly disease. Here we report tumor targeting of a novel internalizing human single chain antibody fragment (scFv) labeled with 99mTc (99mTc-M40) in murine models of mesothelioma of both epithelioid (M28...

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Main Authors: Iyer, Arun K., Lan, Xiaoli, Zhu, Xiaodong, Su, Yang, Feng, Jinjin, Zhang, Xiaoju, Gao, Dongwei, Seo, Youngho, VanBrocklin, Henry F., Broaddus, V. Courtney, Liu, Bin, He, Jiang
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071798/
https://ncbi.nlm.nih.gov/pubmed/21447742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3484
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