Novel human single chain antibody fragments that are rapidly interalizing effectively target epithelioid and sarcomatoid mesotheliomas

Human antibodies targeting all subtypes of mesothelioma could be useful to image and treat this deadly disease. Here we report tumor targeting of a novel internalizing human single chain antibody fragment (scFv) labeled with 99mTc (99mTc-M40) in murine models of mesothelioma of both epithelioid (M28...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Iyer, Arun K., Lan, Xiaoli, Zhu, Xiaodong, Su, Yang, Feng, Jinjin, Zhang, Xiaoju, Gao, Dongwei, Seo, Youngho, VanBrocklin, Henry F., Broaddus, V. Courtney, Liu, Bin, He, Jiang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071798/
https://ncbi.nlm.nih.gov/pubmed/21447742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3484
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk