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Novel human single chain antibody fragments that are rapidly interalizing effectively target epithelioid and sarcomatoid mesotheliomas

Human antibodies targeting all subtypes of mesothelioma could be useful to image and treat this deadly disease. Here we report tumor targeting of a novel internalizing human single chain antibody fragment (scFv) labeled with 99mTc (99mTc-M40) in murine models of mesothelioma of both epithelioid (M28...

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書誌詳細
主要な著者: Iyer, Arun K., Lan, Xiaoli, Zhu, Xiaodong, Su, Yang, Feng, Jinjin, Zhang, Xiaoju, Gao, Dongwei, Seo, Youngho, VanBrocklin, Henry F., Broaddus, V. Courtney, Liu, Bin, He, Jiang
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071798/
https://ncbi.nlm.nih.gov/pubmed/21447742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3484
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