Evidence for Presence and Functional Effects of Kv1.1 Channels in β-Cells: General Survey and Results from mceph/mceph Mice

BACKGROUND: Voltage-dependent K(+) channels (Kv) mediate repolarisation of β-cell action potentials, and thereby abrogate insulin secretion. The role of the Kv1.1 K(+) channel in this process is however unclear. We tested for presence of Kv1.1 in different species and tested for a functional role of...

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Autori principali: Ma, Zuheng, Lavebratt, Catharina, Almgren, Malin, Portwood, Neil, Forsberg, Lars E., Bränström, Robert, Berglund, Erik, Falkmer, Sture, Sundler, Frank, Wierup, Nils, Björklund, Anneli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071710/
https://ncbi.nlm.nih.gov/pubmed/21483673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018213
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