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A TRPM4 Inhibitor 9-Phenanthrol Inhibits Glucose- and Glucagon-Like Peptide 1-Induced Insulin Secretion from Rat Islets of Langerhans

Pancreatic β-cells express several ion channels of the transient receptor potential family, which play important roles in mediating the stimulus-secretion coupling. One of these channels, the TRPM4 is a Ca(2+)-activated monovalent cation channel. This channel is inhibited by 9-phenanthrol, which als...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Ma, Zuheng, Björklund, Anneli, Islam, Md. Shahidul
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643033/
https://ncbi.nlm.nih.gov/pubmed/29098165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5131785
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