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Sequences in the U3 region of Human Immunodeficiency Virus 1 improve efficiency of minus strand transfer in infected cells

A tRNA gene-like sequence has been identified near the 3’ end of HIV-1. Two segments of this sequence (motif 9 and segment 1) promoted minus strand transfer in vitro. The segments are complementary to the tRNA(3)(Lys) primer, and apparently act by binding the tRNA, thereby bringing the 3’ and 5’ end...

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Bibliografski detalji
Glavni autori: Piekna-Przybylska, Dorota, Dykes, Carrie, Demeter, Lisa M., Bambara, Robert A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071581/
https://ncbi.nlm.nih.gov/pubmed/21193211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.11.026
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